We are trying to find out why some ovarian cancer patients don’t respond to chemotherapy. Even though many patients start off well with the treatment, most eventually become resistant to it. When that happens, the only option left is to focus on making the patient comfortable, not curing the cancer.
To solve this problem, we need to understand what causes this resistance so we can develop new treatments. In our study, we found an important factor linked to this resistance by looking at patient data. Early tests suggest this factor might affect immune cells and cause resistance. We will investigate how this factor works and test new ideas using animals, patient samples, and state-of-the-art technologies.