Brian Patrick O’Neill, M.D.

Dr. Brian Patrick O’Neill is the Founding Director of the Mayo Clinic Comprehensive Cancer Center Neuro-Oncology Program and is Director and Overall Principal Investigator of the Mayo Clinic Training Grant in Brain Cancer Research. Dr. O’Neill holds the academic rank of Professor of Neurology. He has served on National Institutes of Health (NIH) Special Review Panels and Search Committees since 1999, and he served as a member of The Cancer Genome Atlas Working Group and the Brain Malignancies Steering Committee. Dr. O’Neill is also a member of the editorial boards of The Journal of Neuro-Oncology and Neuro-Oncology. Dr. O’Neill has been appointed to national committees that deal with scientific review, policy creation and governance and advisory functions. He served on the Executive Committee of the American Academy of Neurology’s Neuro-oncology Section. He is a founding member of the Scientific Advisory Committee of The Sontag Foundation. He is a Charter Member of the Mayo NIH Clinical and Translational Science Award. Dr. O’Neill’s specific research focus is primary CNS lymphoma (PCNSL), and he has led NIH-supported clinical trials and epidemiologic studies in this lethal but potentially curable brain tumor. His current research focus is on the genomic differences between PCNSL and systemic non-Hodgkins lymphoma (NHL) and the development of an animal model.